Landmark, peer-reviewed analysis adds clinical relevance for your everyday practice
- Results reported by sites healthy and plaque-free—as opposed to whole-mouth plaque/gingivitis reduction data—allow you to easily set targets for your practice
- This analysis reviewed data on the additive benefits of LISTERINE® from randomized, observer-blinded, placebo-controlled studies, including both published and unpublished data
- Evidence was drawn from a larger-than-usual population of N>5000 subjects; single studies have an average of 163 subjects
The most robust collection of clinical data of its kind
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![29 Studies of 6 Months’ Duration Over 5000 Patients 3 Countries: United States, Canada & Brazil 4 Decades of Data 500,000+ Sites](https://www.listerine.com.my/sites/listerine_my/files/3.1.1.-image-1.infographic.png)
- 1 landmark analysis: enabled broader, more clinically relevant conclusions
Analysis compared the results of 2 treatment groups
Control group
- Mechanical methods (MM) alone
- 2562 patients
Experimental group
- MM + LISTERINE®
- 2544 patients
Sitewise analysis evaluated efficacy at multiple sites per tooth across the entire mouth
Plaque index (PI): 6 sites per tooth
- Plaque-free sites were defined as those with small pieces of plaque (1) or no plaque (0), based on the PI score
Modified gingival index (MGI): 4 sites per tooth
- Healthy sites were defined as those with mild (1) to no (0) inflammation, based on the MGI scores
LISTERINE® users were more likely to have a cleaner, healthier mouth vs. MM alone
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![LISTERINE® users had nearly 5x more plaque-free sites at 6 months vs. MM alone and over 2x more healthy gingival sites at 6 months vs. MM alone](https://www.listerine.com.my/sites/listerine_my/files/claims_5x_and_2x.png)
LISTERINE® users had more plaque-free sites and more healthy sites — even in the hardest-to-reach areas of the mouth
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![Percentage of patients “plaque-free” by site: LISTERINE® vs. MM alone](https://www.listerine.com.my/sites/listerine_my/files/3.1.1-image-3.png)
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![Percentage of patients “healthy” by gingival site: LISTERINE® vs. MM alone](https://www.listerine.com.my/sites/listerine_my/files/3.1.1-image-4_0.png)
Reference: 1. Araujo MWB, Charles CA, Weinstein RB, et al. Meta-analysis of the effect of an essential oil–containing mouthrinse on gingivitis and plaque. J Am Dent Assoc. 2015;146(8):610-622 and/or post hoc analyses of data.
BIG RESULTS FROM THE BIGGEST LISTERINE® ANALYSIS.
EVER.