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Bold support for

a bold mouthwash

LISTERINE® is an extensively researched mouthwash brand, with over 4 decades of clinical support. Bold evidence like this proves that better oral health is not only possible, but achievable.

 A Comparison of the Effects of 2 Commercially Available Nonprescription Mouthrinses on Salivary Flow Rates and Xerostomia1 

- Kerr AR, Katz RW, Ship JA. A comparison of the effects of 2 commercially available nonprescription mouthrinses on salivary flow rates and xerostomia. Quintessence Int. 2007;38(705):41-48.

 ACT® Mouthwash vs LISTERINE® Effects on Dry Mouth 

 Objective 

To determine if 2 commercial mouthrinses, 1 alcohol-based (LISTERINE® COOL MINT®) and 1 nonalcohol-based (Act® Anticavity Fluoride Mouthwash—Alcohol Free, Mint), affect salivary flow and symptoms of dry mouth in nonxerostomic adults (N=20).

 Methodology 

Observer-blinded, randomized, crossover study of nonxerostomic subjects (aged 18-85 years).

 Results 

After 1 week of mouthrinse use, combined data (before and after crossover) revealed no significant differences in flow rates between groups (P>0.05).

 Conclusion 

“There were no differences in objective or subjective measures of mouth dryness between alcohol- and nonalcohol-containing mouthrinses after 1 week in nonxerostomic subjects.”*

*LISTERINE® is not indicated for use in the treatment of xerostomia.
Nonalcohol based.

 Reference: 1.  Kerr AR, Katz RW, Ship JA. A comparison of the effects of 2 commercially available nonprescription mouthrinses on salivary flow rates and xerostomia. Quintessence Int. 2007;38(705):41-48.

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Site last updated: July 06, 2026

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Always seek the advice of your physician, dental professional, or other qualified health provider with any questions you may have regarding a medical/dental condition.