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Bold fact: LISTERINE® is an extensively

researched mouthwash brand.

With a history steeped in science, technical innovation, and partnership with dental professionals to achieve better outcomes for patients, LISTERINE® Mouthwash stands as a bold leader in oral care—just as it did 137 years ago. LISTERINE® has been studied in more than 30 clinical trials, making it the clear choice when recommending a mouthwash to patients.

What's bolder than better oral health?
What's bolder than better oral health?

The Proof it's possible.

Review publications

4 Essential Oils.
4 Essential Oils.

1 Bold Mouthwash.

See the science

LISTERINE®
LISTERINE®

vs. Other Rinses

See how they stack up

Studied for Safety.
Studied for Safety.

Used for Boldness.

Learn more

References:1. Gunsolley, JC. A meta‐analysis of six‐month studies of antiplaque and antigingivitis agents. J Am Dent Assoc. 2006;137(12):1649‐1657. 2. Gunsolley JC, Clinical efficacy of antimicrobial mouthrinses. J Dent. 2010;38(suppl 1):S6‐S10. 3. Van Leeuwen MP, Slot DE, Van der Weijden GA. Essential oils compared with respect to plaque and parameters of gingival inflammation: a systematic review. J Periodontol. 2011;82(2):174‐194. 4. Swango PA. Regular use of antimicrobial mouthrinses can effectively augment the benefits of oral prophylaxis and oral hygiene instructions at 6-month recall intervals in reducing the occurrence of dental plaque and gingivitis. J Evid Based Dent Pract. 2012;12(2):87‐89. 5. Boyle P, Koechlin A, Autier P. (The International Prevention Research Institute, France). Mouthwash use and the prevention of plaque, gingivitis and caries. Oral Dis. 2014;20(suppl 1):1‐68.

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Site last updated: July 06, 2026

Disclaimer: Advice on oral care provided on this site is not intended as a substitute for professional medical/dental advice, diagnosis, or treatment.

Always seek the advice of your physician, dental professional, or other qualified health provider with any questions you may have regarding a medical/dental condition.